艺颂金亨泰院长在耳鼻咽喉最具有权威的学术杂志The Laryngoscope 上发表了关于喉乳头瘤治疗的相关新方法和临床治疗效果的相关论文.
论文以艺颂十多年的临床经验为依托，从理论上系统的总结了艺颂新方法对患者治疗所带来的良好疗效，对整个喉乳头瘤疾病的治疗带来了新的理念和治愈希望！
论文研究的主题 : Is Recurrent Respiratory Papillomatosis a Manageable or Curable Disease?
论文 提名: Laryngoscope, 126:1359–1364, 2016
内容摘要 :
Objectives: Recurrent respiratory papillomatosis (RRP) is a relatively rare disease with potentially devastating consequences for the patient. The purpose of this study was to evaluate the patterns of recurrence of RRP after surgery and determine the effectiveness of combined concurrent adjuvant therapy.
Methods: A total of 86 patients were diagnosed with and operated on for RRP. The clinical characteristics of 29 of the 86 patients who had undergone operations at other hospitals and who were followed up for >2 years were evaluated retrospectively. A combined concurrent adjuvant therapy was performed with microlaryngeal surgery, 585-nm pulsed dye laser (PDL) application, and an intralesional cidofovir injection. To evaluate the recurrence pattern, the larynx was divided into 10 subsites, and patients were investigated for the frequency of recurrence at the subsites after the operation.
Results: Twenty-nine subjects required a mean of 3.0 operations to achieve complete remission for 2 years. The most common subsites for recurrence were the anterior commissure, subglottis, and epiglottis according to increasing number of operations. The subsites of recurrence tended to be closely correlated with the laryngeal submucosal glandular density distribution. A complete en-bloc layer excision, including the submucosal glands, using cold instruments decreased the recurrence rate of RRP. Applying PDL minimized scarring and provided significant posttreatment voice-quality improvement.
Conclusions: The results of the recurrent pattern analysis suggest that a combined concurrent adjunctive treatment might be promising as a cure for RRP and restoration of vocal function after treatment.
.png)
|